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Vasilis Ntziachristos Profile Page
Vasilis Ntziachristos
Research Area: Imaging
Research Topic: Development of in-vivo imaging technology from basic research to clinical application.
Research Summary: The Institute for Biological and Medical Imaging (IBMI) plays a central role in engineering necessary technology and work-platforms that enable in-vivo imaging from living micro-organisms to humans. With strategic locations at the Helmholtz Munich Center campus and the Technical University of Munich Medical School and Hospital, the institute further connects basic research and clinical need and serves as an educational unit in imaging technology and application. To achieve these goals, IBMI integrates highly interdisciplinary skills and bridges mathematics, physics, engineering, chemistry, biology and medicine and invests in key focus areas, including the development of new imaging devices and multi-modality systems, advancing imaging and image reconstruction theories and methods, development of animal models for the interrogation of new technologies at the biological, pre-clinical and clinical level and advanced data and image processing methods and medical informatics. Key application areas include the development of new tools for the biomedical laboratory as well as the investigation of imaging methods for diagnostic and disease monitoring and treatment in key areas including cancer, inflammation, cardiovascular and neurodegenerative disease.
Lab website: www.cbi.ei.tum.de/
Selected Publications: 1.Ntziachristos V., “Going deeper than optical microscopy: High resolution photonic molecular imaging for next generation biology” Nature Methods, in press (2010)

2.Razansky D, Vinegoni C, Distel M, Ma R, Perrimon N, Koster RW, Ntziachristos V., “Going deeper than microscopy with multi-spectral optoacoustic tomography of fluorescent proteins in-vivo”, Nature Photonics 3, 412-417 (2009)

3.Vinegoni C., Pitsouli C., Razansky D.,Perrimon N., Ntziachristos V., “Live imaging of Drosophila pupae with Mesoscopic Fluorescence Tomography” Nature Methods, 5(1):45-7 (2008).

4.Niedre MJ, de Kleine RH, Aikawa E, Kirsch DG, Weissleder R, Ntziachristos V Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo. P Natl Acad Sci U S A. 105(49):19126-31 (2008).

5.Sosnovik D, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, Rosenzweig A, Weissleder R, Ntziachristos V, “Fluorescence Tomography and Magnetic Resonance Imaging of Myocardial Macrophage Infiltration in Infarcted Myocardium In Vivo” Circulation 115(11):1384-91 (2007).

6.Ripoll J, Ntziachristos V., “From finite to infinite volumes: Removal of boundaries in diffuse wave imaging” Phys. Rev. Letters 96(17):173909 (2006).

7.Ntziachristos V, Ripoll J, Wang L, Weissleder R., “Looking and listening to light: the revolution of photonic imaging” Nature Biotechnology 23(3): 313-320 (2005).